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NachrichtenLexikonProtokolleBücherForenDienstag, 23. September 2014 

Therapeutic Interventions in the Complement System (Contemporary Immunology)


von John D. Lambris

Kategorie: Immunologie
ISBN: 0896035875

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From Book News, Inc. Reviews complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in cases where its inappropriate activation produces cell damage. Each chapter focuses on a specific area of basic and applied complement biology, spelling out activation pathways and complement receptors. Animal models are discussed in detail, including values of each model and important interspecies differences. Emphasis is on pros and cons of the use of recombinant complement inhibitors in specific diseases. Lambris is affiliated with the University of Pennsylvania School of Medicine. Holers is affiliated with the University of Colorado Health Science Center.Book News, Inc.®, Portland, OR

Synopsis The complement (C') system is a complex group of proteins and glycoproteins which together play an important role in host defence against infection. This text provides an overview of interest to those interested in manipulation of the complement system in a therapeutic setting. The book takes a disease-orientated approach by focusing on the manipulation of complement in various diseases such as ischemia-reperfusion injury in addition to systemic and organ-specific inflammatory and autoimmune...


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