Insulin Resistance: the Metabolic Syndrome X
From Book News, Inc. Reaven, who discovered Syndrome X, assembles summaries of the current understanding of how insulin resistance and its compensating hyperinsulinemia play a major role in the pathogenesis and clinical course of high blood pressure, cardiovascular disease, and polycystic ovary syndrome. They detail the pathophysiological consequences and the clinical syndromes besides Type 2 diabetes that are related to insulin resistance, and explore the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Of interest to both researchers and clinicians. Book News, Inc.®, Portland, OR
Synopsis Himsworth's 1936 paper introduced the idea that resistance to insulinmediated glucose disposal could play a role in human disease. Although the medical community supports this notion that insulin resistance plays a central role in the aetiology of Type 2 diabetes, the contributors agree with Himsworth in that the importance of insulin resistance in human disease far trascends this single purpose. The insulin resistance approach allows the authors to make noncritical summaries of the topics...