Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery : Electrically Mediated Delivery of Molecules to Cells (Methods in Molecular me

von Mark J. Jaroszeski Kategorie: Zellbiologie ISBN: 0896036065 Kommentar abgeben

From Book News, Inc. Reviews all aspects of the delivery of therapeutic molecules to cells using electrical impulse. Surveys basic physical principles that govern cell permeabilization by pulsed electric fields, describes instrumentation and electrodes, and summarizes preclinical and clinical trial results. Focuses on drug, gene, and transdermal delivery techniques, providing detailed examples of drug delivery using electric fields from a variety of pulse generators and electrodes. Jaroszeski is affiliated with the U. of South Florida College of Medicine.Book News, Inc.®, Portland, OR

Synopsis The use of electricity to mediate the delivery of molecules to cells in vivo is a growing application of our greater ability to deliver drugs, DNA, antibodies and proteins into the cells of living organisms. This volume provides the techniques and methods for in vivo electroporation covering electrochemotherapy, electrogenetherapy, and transdermal delivery of pharmacological agents by electroporation. The first section of this manual reviews the critical aspects of electroporation,...