Molecular Mechanisms of Neurodegenerative Diseases
|von Md Marie-Francoise Chesselet|
From Book News, Inc. Researchers and neurologists from industry and academia critically review recent advances in the study of Alzheimer's, Parkinson's, and CAG triplet repeat diseases from various points of view, showing how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and could lead to new therapies. Topics covered include the role of glial cells and inflammation in Alzheimer's disease; the impact of dopamine and mitochondrial dysfunction on neurodegeneration; the pathophysiology of spinal and bulbar muscular atrophy; mouse models of Huntington's Disease; and modeling neurodegenerative diseases in the fruit fly. Of likely interest to physicians, neuroscientists, neurologists, and cell biologists.Book News, Inc.®, Portland, OR
Synopsis The last few years have seen unprecedented progress in our understanding of the basic processes that lead to neuronal dysfunction and death in neurodegenerative diseases. An unexpected finding is the emergence of common mechanisms that could play a role in diseases previously thought to be distinct such as Alzheimer's, Parkinson's and Huntington's diseases. This book presents integrated coverage of recent advances in the molecular mechanisms of neurodegenerative diseases and describes how these...
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